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New treatment option for Symptom, Cognitive
Official title Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate
ClinicalTrials.gov ID: NCT06340789
What this study is testing
What is Sodium Benzoate 2gram/day?
Sodium Benzoate 2gram/day is an investigational medicine, being studied as a potential treatment for symptom, cognitive.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Although antipsychotic is effective for schizophrenia, however, still certain proportion of patients were not responsive to treatment. Treatment resistant schizophrenia (TRS) is accompanied by function decline and heavy burden.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 55
You may be able to join if
- Fulfil the DSM5 criteria for schizophrenia or schizoaffective disorder
- Research criteria for treatment resistance: little or no symptomatic response to multiple (at least two) antipsychotic treatment of an adequate...
- 6 month period without remission (i.e. ≥4 item-score for the positive symptoms on PANSS scale , especially delusional thoughts, conceptual...
- The persistence of illness was defined as a score of ≥4 (moderately ill) on the severity of illness subscale of the Clinical Global Impression scale...
You likely can't join if
- Current or previous diagnosis of concurrent DSM-5 disorder due to active medical problems, known neurological disease, or a contraindication to MRI...
- Current diagnosis of substance-related disorder
- Any acute or chronic medical condition
- History of head trauma or neurological diseases.
The study team makes the final eligibility decision.
Where it's taking place
- Chiayi City, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 55 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chiayi City, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.