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New treatment option for Hypertension
Official title Isometric Handgrip Training Frequency and Blood Pressure in People With Hypertension
ClinicalTrials.gov ID: NCT06335433
What this study is testing
- What it's testing
- Hypertension is the most important cause of cardiovascular disease (CVD), stroke, and premature death (WHO, 2021). It is estimated by The World Health Organisation in 2021 that 1.4 billion individuals across the globe have high blood pressure, with only 14% of people actively managing these elevated levels.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Aged between 18 and 65 years.
- Scoring low or moderate on the international physical activity questionnaire (IPAQ).
- Previous diagnosis of high blood pressure and/or a resting systolic blood pressure ≥130 but \<180 mmHg (self-reported and confirmed during...
- Currently taking no anti-hypertensive medicine or taking anti-hypertensive medicine with no treatment change within the last 4 months prior to...
- Stable dietary and physical activity patterns (including dietary supplementation) over the last 4 months
You likely can't join if
- Aged \ 65 years
- Resting blood pressure ≥180/110 mmHg or resting heart rate \>100 bpm during baseline as-sessment
- Manifest cardiovascular disease including cerebrovascular disease, heart failure, chronic kidney disease, peripheral vascular disease, or advanced...
- Type 1 diabetes
- History of other chronic disease including malignancy, neurological conditions (e.g. multiple sclerosis) or respiratory conditions (e.g. COPD).
- Contraindications to exercise based on answers to the physical activity readiness questionnaire.
See the full eligibility criteria
- Aged between 18 and 65 years.
- Scoring low or moderate on the international physical activity questionnaire (IPAQ).
- Previous diagnosis of high blood pressure and/or a resting systolic blood pressure ≥130 but \<180 mmHg (self-reported and confirmed during screening/baseline assessment).
- Currently taking no anti-hypertensive medicine or taking anti-hypertensive medicine with no treatment change within the last 4 months prior to enrollment.
- Stable dietary and physical activity patterns (including dietary supplementation) over the last 4 months
- Aged \ 65 years
- Resting blood pressure ≥180/110 mmHg or resting heart rate \>100 bpm during baseline as-sessment
- Manifest cardiovascular disease including cerebrovascular disease, heart failure, chronic kidney disease, peripheral vascular disease, or advanced retinopathy (fundus hypertonicus grades III-IV) based on a self-report...
- Type 1 diabetes
- History of other chronic disease including malignancy, neurological conditions (e.g. multiple sclerosis) or respiratory conditions (e.g. COPD).
- Contraindications to exercise based on answers to the physical activity readiness questionnaire.
- Physical limitations preventing handgrip exercise (e.g. arthritis or other musculoskeletal disorder)
- Scoring "high" on the international physical activity questionnaire
- Taking more than 2 anti-hypertensive drugs or a change in treatment strategy in the previous 4 months.
- Currently taking nitrate medication (as it is commonly prescribed for angina) or on hormone replacement therapy
- Significant self-reported change in lifestyle patterns in the prior 4 months (e.g. currently on a planned diet for weight loss).
The study team makes the final eligibility decision.
Where it's taking place
- Swansea, Wales, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Swansea, Wales, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.