BridgeMD
New treatment option for Heart Failure, Systolic
Official title Paced Heart Rate Acceleration for Cardiac Conditioning
ClinicalTrials.gov ID: NCT06332391
What this study is testing
- What it's testing
- A clinical trial of exercise-similar heart rate acceleration delivered via cardiac pacing vs. sham intervention in subjects at rest will be performed.
- Time commitment: about 1 month
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 120
You may be able to join if
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female sex
- Age 18 years or greater
- Available transportation for study visits
You likely can't join if
- Age \< 18 years
- Inability to ambulate safely
- Congenital or primary valve disease
- Ongoing (not suppressed) atrial arrhythmias
- Left ventricular thrombus
- Severe peripheral arterial disease that limits mobility
See the full eligibility criteria
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female sex
- Age 18 years or greater
- Available transportation for study visits
- Left ventricular ejection fraction \< or = 40% despite at least 3 months guideline-directed medial therapy
- NYHA class II-III heart failure symptoms
- Atrial-lead inclusive implantable cardioverter defibrillator or biventricular defibrillator in place \> 3 months
- Intrinsic or biventricular paced QRS duration of \<= 120 milliseconds
- Age \< 18 years
- Inability to ambulate safely
- Congenital or primary valve disease
- Ongoing (not suppressed) atrial arrhythmias
- Left ventricular thrombus
- Severe peripheral arterial disease that limits mobility
- Hospital admission for life-threatening condition (e.g. heart failure, stroke) in the past 3 months
- Major surgery in the past 3 months or anticipated during the period of study
- Ventricular pacing indication in the absence of biventricular pacing
- Life expectancy \< 1 year
- Hemodialysis
- Hematocrit \< 30%
- Severe chronic lung disease that limits activity or requires oxygen
- Pregnancy
- Implantable cardioverter defibrillator battery longevity \< 1 year
- Vulnerable populations such as prisoners and institutionalized individuals
The study team makes the final eligibility decision.
Where it's taking place
- Iowa City, Iowa, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 1 month per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 120 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Iowa City, Iowa, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.