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New treatment option for Intermittent Fasting
Official title Longitudinal Monitoring During Intermittent Fasting Protocols in Obese Adults
ClinicalTrials.gov ID: NCT06323889
What this study is testing
- What it's testing
- LIMITFOOD2 is a randomized clinical intervention study that investigates the effects of two different intermittent fasting protocols compared to a control group on the health of obese adults. A total of 90 participants will be randomized into three equally sized groups: a modified alternate day fasting, a time-restricted eating and a control group, receiving general weight-loss counseling.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50. Healthy volunteers may be eligible.
You may be able to join if
- Age between 18-50 years, both inclusive
- Obese, BMI between 30 and 40 kg/m\^2 (obesity grade I or II), both inclusive
- Non-smoker
- Good knowledge of German or English language
- Stable weight change (change \< +/- 3% current bodyweight) for 3 months prior to the study
You likely can't join if
- Participants who have a fasting period of \> 12h per day on a regular basis and do not eat at least three main meals per day.
- Current habitual use of dietary supplements (e.g., vitamins, minerals) and/or unwillingness to cease intake of dietary supplements.
- Antibiotics intake during 3 months prior to the study due to possible interference with metabolic parameters
- Food intolerances, allergies and sensitivities (severe food allergies) or dietary restrictions (e.g. vegan lifestyle)
- Acute or chronic infections, malignant disease, renal, hepatic (more than two-fold increased transaminases), pulmonary, neurological (epilepsy) or...
- Diabetes
See the full eligibility criteria
- Age between 18-50 years, both inclusive
- Obese, BMI between 30 and 40 kg/m\^2 (obesity grade I or II), both inclusive
- Non-smoker
- Good knowledge of German or English language
- Stable weight change (change \< +/- 3% current bodyweight) for 3 months prior to the study
- HbA1c \< 6.5% without glucose lowering medication
- LDL-cholesterol \< 4.6mmol/l without lipid lowering medication
- Participants who have a fasting period of \> 12h per day on a regular basis and do not eat at least three main meals per day.
- Current habitual use of dietary supplements (e.g., vitamins, minerals) and/or unwillingness to cease intake of dietary supplements.
- Antibiotics intake during 3 months prior to the study due to possible interference with metabolic parameters
- Food intolerances, allergies and sensitivities (severe food allergies) or dietary restrictions (e.g. vegan lifestyle)
- Acute or chronic infections, malignant disease, renal, hepatic (more than two-fold increased transaminases), pulmonary, neurological (epilepsy) or psychiatric diseases, manifested atherosclerosis, or any other disease...
- Diabetes
- Known alcohol, substance or drug abuse, concomitant medication
- More than four hours of physical exercise per week
- Women who are pregnant, breast-feeding or aiming to become pregnant during course of the trial
- Women and men on hormonal supplementation
- Women with an irregular menstrual cycle according to the FIGO criteria
- Therapy with antidepressants within the past 6 months
- Regular therapy with acetylsalicyclic acid or current medication to regulate blood sugar, blood pressure or lipids
- Participants likely to fail to comply with the study protocol
- Participants who do not give informed consent
The study team makes the final eligibility decision.
Where it's taking place
- Zurich, Canton of Zurich, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Zurich, Canton of Zurich, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.