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New treatment option for Pain, Acute
Official title Effect of Vitamin C on Pain Reduction After an Emergency Department Visit
ClinicalTrials.gov ID: NCT06306183
What this study is testing
- What it's testing
- Musculoskeletal (MSK) injuries such as sprains, strains, bruises, and fractures are among the most common reasons people visit the emergency department. These injuries often cause significant pain in the first few days, making it difficult to move, work, or sleep.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years old
- Presenting to the ED with acute MSK pain of ≤ 48 hours duration at triage
- Verbal numerical rating scale pain intensity at triage of ≥ 4 on a 0-10 scale
- Triaged to the ambulatory section of the ED
- Able to communicate in French or English
You likely can't join if
- Usage of Vit C supplements in the last week
- Active cancer
- Treated with opioids for any pain within 24 hours prior to recruitment
- Treatment for chronic pain
- Unable to fill out a pain intensity diary or unavailable for follow-up
- Allergy to milk (lactose in the placebo) or Vit C
See the full eligibility criteria
- Age ≥ 18 years old
- Presenting to the ED with acute MSK pain of ≤ 48 hours duration at triage
- Verbal numerical rating scale pain intensity at triage of ≥ 4 on a 0-10 scale
- Triaged to the ambulatory section of the ED
- Able to communicate in French or English
- Usage of Vit C supplements in the last week
- Active cancer
- Treated with opioids for any pain within 24 hours prior to recruitment
- Treatment for chronic pain
- Unable to fill out a pain intensity diary or unavailable for follow-up
- Allergy to milk (lactose in the placebo) or Vit C
- Treated with cyclosporine or warfarin
- Pre-existing oxalate nephropathy, liver cirrhosis or hemochromatosis
- Hospitalized after clinician evaluation
The study team makes the final eligibility decision.
Where it's taking place
- Ottawa, Ontario, Canada
- Lévis, Quebec, Canada
- Montreal, Quebec, Canada
- Québec, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ottawa, Ontario, Canada; Lévis, Quebec, Canada; Montreal, Quebec, Canada; Québec, Quebec, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.