BridgeMD
New treatment option for Anesthesia
Official title End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children
ClinicalTrials.gov ID: NCT06303518
What this study is testing
- What it's testing
- Carbon Dioxide (CO2) is a by-product of metabolism and is removed from the body when we breathe out. High levels of CO2 can affect the nervous system and cause us to be sleepy or sedated.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 11. Healthy volunteers may be eligible.
You may be able to join if
- Children aged 3 - 11 years undergoing non- or minimally-stimulating elective procedures, defined as anesthesia without skin incision or painful...
- American Society of Anesthesiologists (ASA) physical status I and II
- TIVA technique appropriate throughout induction and maintenance of anesthesia
- Controlled ventilation via endotracheal tube
- Anticipated surgical time ≥ 90 minutes: to allow time for anesthetic induction and subsequent testing and washout periods at all three EtCO2 levels.
You likely can't join if
- Need for inhalational induction of anesthesia
- Sedative premedication
- Use of ketamine intraoperatively
- Unable to place BIS electrodes due to surgical site or other contraindications (e.g., MRI)
- Allergy to study drugs (propofol, remifentanil, lidocaine)
- Depression of conscious level for any reason
See the full eligibility criteria
- Children aged 3 - 11 years undergoing non- or minimally-stimulating elective procedures, defined as anesthesia without skin incision or painful manipulation (e.g., non-invasive imaging, auditory brainstem response...
- American Society of Anesthesiologists (ASA) physical status I and II
- TIVA technique appropriate throughout induction and maintenance of anesthesia
- Controlled ventilation via endotracheal tube
- Anticipated surgical time ≥ 90 minutes: to allow time for anesthetic induction and subsequent testing and washout periods at all three EtCO2 levels.
- Need for inhalational induction of anesthesia
- Sedative premedication
- Use of ketamine intraoperatively
- Unable to place BIS electrodes due to surgical site or other contraindications (e.g., MRI)
- Allergy to study drugs (propofol, remifentanil, lidocaine)
- Depression of conscious level for any reason
- BMI \ 95th centile for age
- History of obstructive or central sleep apnea
- Known or suspected raised intracranial pressure
- Recent or historical traumatic brain injury
The study team makes the final eligibility decision.
Where it's taking place
- Vancouver, British Columbia, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years to 11 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Vancouver, British Columbia, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.