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New treatment option for Subthreshold Depression
Official title TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
ClinicalTrials.gov ID: NCT06294184
What this study is testing
- What it's testing
- The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is carried out.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 25. Healthy volunteers may be eligible.
You may be able to join if
- 1) Be between the ages of 12-25;
- 2) is right-handed on the Edinburgh Handedness Inventory;
- 3) 2-4 of the 9 depressive symptoms defined by the American Diagnostic and Statistical Manual of Diseases, Fifth Edition (DSM-5), lasting more than 1...
- 4) Hamilton Depression Scale (HAMD-24) 24 points≥ 8 points, \< 24 points;
- 5) Gender is not limited;
You likely can't join if
- 1) Individuals with the following diagnoses according to DSM-5: psychiatric disorders due to organic diseases, substance-related and addictive...
- 2) Have two or more DSM-V-defined manic symptoms for 4 days but do not meet the criteria for hypomania or meet the DSM-V defined criteria for...
- 3) Severe or unstable physical illness;
- 4) have a moderate or higher risk of suicide (as assessed by the Columbia Suicide Severity Scale);
- 5) Received transcranial direct current stimulation in the past three months (continuous intervention time: \>2 weeks);
- 6) Contraindications to transcranial direct current stimulation, such as brain implants, personal or family history of epilepsy;
See the full eligibility criteria
- 1) Be between the ages of 12-25;
- 2) is right-handed on the Edinburgh Handedness Inventory;
- 3) 2-4 of the 9 depressive symptoms defined by the American Diagnostic and Statistical Manual of Diseases, Fifth Edition (DSM-5), lasting more than 1 week; or more than 5 depressive symptoms lasting more than 1 week but...
- 4) Hamilton Depression Scale (HAMD-24) 24 points≥ 8 points, \< 24 points;
- 5) Gender is not limited;
- 6) people and their families voluntarily participate and sign the informed consent form.
- 1) Individuals with the following diagnoses according to DSM-5: psychiatric disorders due to organic diseases, substance-related and addictive disorders, neurodevelopmental disorders, schizophrenia spectrum and other...
- 2) Have two or more DSM-V-defined manic symptoms for 4 days but do not meet the criteria for hypomania or meet the DSM-V defined criteria for hypomanic symptoms for only 2-3 days;
- 3) Severe or unstable physical illness;
- 4) have a moderate or higher risk of suicide (as assessed by the Columbia Suicide Severity Scale);
- 5) Received transcranial direct current stimulation in the past three months (continuous intervention time: \>2 weeks);
- 6) Contraindications to transcranial direct current stimulation, such as brain implants, personal or family history of epilepsy;
- 7) Magnetic resonance scanning is contraindicated, such as in vivo metal implants.
The study team makes the final eligibility decision.
Where it's taking place
- Guangzhou, Guangdong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years to 25 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guangzhou, Guangdong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.