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New treatment option for Childhood Depression
Official title Neural Mechanisms of Family-Focused Treatment for Youth Depression
ClinicalTrials.gov ID: NCT06289010
What this study is testing
- What it's testing
- The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it aims to answer are: What are differences between depressed and non-depressed participants on baseline neural and parenting indicators?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 7 to 12. Healthy volunteers may be eligible.
You may be able to join if
- Children must:
- Have a current DSM-5 diagnosis of MDD, Persistent DD, or DDNOS (based on K-SADS-PL) OR not meet criteria for any DSM-5 mental health diagnosis (based...
- Be ages 7-12
- Be living with a parent(s) or guardian willing to participate
- Be able and willing to provide informed consent/assent Parent must:
You likely can't join if
- Thought or other disturbance in the child that would interfere with the ability to participate in treatment or assessments (e.g., psychotic disorder...
- Severe conduct disorders in the child that threaten the home stability (e.g. juvenile justice or children's protective service involvement as...
- Youth or primary caregivers do not speak English
- Either parent or child has contraindications for neuroimaging (e.g., claustrophobia, metal implants, braces, electronically, magnetically, or...
- The child is on an antidepressant medication, as it may complicate neuroimaging interpretation.
See the full eligibility criteria
- Children must:
- Have a current DSM-5 diagnosis of MDD, Persistent DD, or DDNOS (based on K-SADS-PL) OR not meet criteria for any DSM-5 mental health diagnosis (based on K-SADS-PL)
- Be ages 7-12
- Be living with a parent(s) or guardian willing to participate
- Be able and willing to provide informed consent/assent Parent must:
- Not be currently pregnant
- Be able to read, understand consent forms, and provide consent on their child's behalf
- Be the biological parent (or grandparent in parental role) of the participating child \& have lived with the child for more than 75% of the child's life. All participants must:
- Not have a disturbance that would interfere with participation such as autism spectrum disorder, psychosis, current substance dependence, current use of psychotropic medication, OCD, or MRI contraindication such as...
- Be proficient in English
- Thought or other disturbance in the child that would interfere with the ability to participate in treatment or assessments (e.g., psychotic disorder, autism spectrum disorder, OCD, active substance abuse/dependence...
- Severe conduct disorders in the child that threaten the home stability (e.g. juvenile justice or children's protective service involvement as assessed on KSADS-PL) due to the potential impact on retention
- Youth or primary caregivers do not speak English
- Either parent or child has contraindications for neuroimaging (e.g., claustrophobia, metal implants, braces, electronically, magnetically, or mechanically activated devices such as cochlear implants)
- The child is on an antidepressant medication, as it may complicate neuroimaging interpretation.
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
- Charlestown, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 7 years to 12 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States; Charlestown, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.