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New treatment option for Chronic Kidney Diseases
Official title Beetroot Extract Supplementation Associated With an Exercise Protocol for Chronic Kidney Disease Patients
ClinicalTrials.gov ID: NCT06286748
What this study is testing
- What it's testing
- Chronic kidney disease (CKD) patients often present systemic inflammation and oxidative stress, resulting in metabolic disorders and high rates of disease-associated cardiovascular death. The literature has indicated that dietary control, the use of bioactive compounds, and the practice of regular physical exercise are essential for the prevention and management of CKD and its complications.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Patients with CKD undergoing conservative treatment (stages G3a-G4);
- Aged between 18 and 65 years old;
- Patients undergoing nutritional monitoring for more than 6 months.
You likely can't join if
- Patients using catabolic drugs;
- Smokers
- Pregnant women;
- Using antibiotics and of proton pump inhibitors in the last 3 months;
- Antioxidant supplements and habitual intake of beetroot or nitrate supplement;
- Those who are clinically unstable (unstable angina, atrial fibrillation, significant cardiac arrhythmia and acute illness in the last month; and...
See the full eligibility criteria
- Patients with CKD undergoing conservative treatment (stages G3a-G4);
- Aged between 18 and 65 years old;
- Patients undergoing nutritional monitoring for more than 6 months.
- Patients using catabolic drugs;
- Smokers
- Pregnant women;
- Using antibiotics and of proton pump inhibitors in the last 3 months;
- Antioxidant supplements and habitual intake of beetroot or nitrate supplement;
- Those who are clinically unstable (unstable angina, atrial fibrillation, significant cardiac arrhythmia and acute illness in the last month; and glycemic lability);
- Unable to exercise (amputation without prosthesis); musculoskeletal pain at rest or with minimal physical activity, inability to sit or walk without assistance, use of a walking device, dyspnea at rest or with light...
- Those with autoimmune diseases and infectious diseases, cancer, liver disease and AIDS.
- Patients with parathormone (PTH) levels above 500pg/mL;
- Those who are allergic or intolerant to the components of the juice.
- Patients with any impediment to completing the proposed exercise protocol, such as due to travel or difficulty accessing the location where the research will be carried out.
The study team makes the final eligibility decision.
Where it's taking place
- Rio de Janeiro, Rio de Janeiro, Brazil
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rio de Janeiro, Rio de Janeiro, Brazil. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.