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New treatment option for Depression
Official title Positive Affect Treatment for Adolescents With Early Life Adversity
ClinicalTrials.gov ID: NCT06273137
What this study is testing
- What it's testing
- Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today. Youth exposed to ELA consistently report symptoms of anhedonia as well as dysregulated positive affect.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 16. Healthy volunteers may be eligible.
You may be able to join if
- aged 12-16
- exposed to 2 or more adverse childhood experiences (ACEs)
You likely can't join if
- currently taking an antidepressant or any medications known to influence immune functioning on a daily basis (e.g., steroidal medications to treat...
- current or past history of manic or psychotic symptoms
- parent-reported diagnosis of intellectual disability or autism spectrum disorder
- chronic medical conditions (e.g., cancer, rheumatoid arthritis, diabetes, multiple sclerosis),
- bleeding disorders such as hemophilia
The study team makes the final eligibility decision.
Where it's taking place
- Irvine, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years to 16 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Irvine, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.