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Compares treatment options for Colorectal (Colon or Rectal) Cancer
Official title Comparison of Intravenous Lidocaine vs Ketamine in Colorectal Surgery
ClinicalTrials.gov ID: NCT06272461
What this study is testing
What is Lidocaine IV?
Lidocaine IV is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for colorectal (colon or rectal) cancer.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Patients undergoing open colorectal surgery were randomly divided into two groups: Intravenous Lidocaine (IV-Lido) vs Intravenous Ketamine (IV-Keta). For the IV-Lido group, patients received a loading dose of Lidocaine than a continuous infusion over twenty-four hours.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Patients aged 18 or older.
- American society of anesthesiologists' (ASA) physical status of I-III.
- Elective open colorectal surgery. NON
- Patients with contraindications to lidocaine or ketamine.
- Corticosteroid therapy within the last 6 months.
You likely can't join if
- Severe intraoperative complications.
- Duration of surgery longer than 5 hours.
See the full eligibility criteria
- Patients aged 18 or older.
- American society of anesthesiologists' (ASA) physical status of I-III.
- Elective open colorectal surgery. NON
- Patients with contraindications to lidocaine or ketamine.
- Corticosteroid therapy within the last 6 months.
- History of immunosuppressive therapy.
- History of surgery in the last 3 months.
- Personal medical history of inflammatory bowel disease.
- Personal medical history of cardiac arrythmias or conduction disorders.
- Alcohol or drug abuse.
- Chronic use of opioids or benzodiazepines.
- Severe intraoperative complications.
- Duration of surgery longer than 5 hours.
The study team makes the final eligibility decision.
Where it's taking place
- Nabeul, Tunisia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nabeul, Tunisia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.