BridgeMD
New treatment option for Metabolic Syndrome
Official title Strategic Lifestyle Intervention for Metabolic Syndrome (SLIM-MET)
ClinicalTrials.gov ID: NCT06271200
What this study is testing
- What it's testing
- This study is a randomized, parallel-group, observer-masked clinical trial. A total of 200 obese participants with MetS will be enrolled.
- Time commitment: about 24 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 65
You may be able to join if
- Men or women aged from ≥ 20 years to 65 years
- BMI 27.0 to 45.0 kg/m2 with metabolic syndrome by IDF definition
You likely can't join if
- History of HIV, hepatitis B or C (self-report) or active pulmonary tuberculosis
- Diagnosis of type 1 or type 2 diabetes and regular taking oral or injection hypoglycemic therapy
- History of malignant tumors with active managements.
- History of medullary thyroid carcinoma or diagnosis of multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Serious liver dysfunction or chronic kidney disease (aspartate aminotransferase (AST) or alanine transaminase (ALT) \> 3 times the upper limit of...
- History of serious cardiovascular or cerebrovascular disease (angina, myocardial infarction or stroke) in the past 6 months History of severe...
See the full eligibility criteria
- Men or women aged from ≥ 20 years to 65 years
- BMI 27.0 to 45.0 kg/m2 with metabolic syndrome by IDF definition
- History of HIV, hepatitis B or C (self-report) or active pulmonary tuberculosis
- Diagnosis of type 1 or type 2 diabetes and regular taking oral or injection hypoglycemic therapy
- History of malignant tumors with active managements.
- History of medullary thyroid carcinoma or diagnosis of multiple endocrine neoplasia syndrome type 2 (MEN 2)
- Serious liver dysfunction or chronic kidney disease (aspartate aminotransferase (AST) or alanine transaminase (ALT) \> 3 times the upper limit of normal, or estimated glomerular filtration rate (eGFR) \< 30 ml/min/1.73...
- History of serious cardiovascular or cerebrovascular disease (angina, myocardial infarction or stroke) in the past 6 months History of severe gastrointestinal diseases or gastrointestinal surgery in the past 6 months
- History of Cushing's syndrome, hypothyroidism, acromegaly, hypothalamic obesity without regular managements.
- History of hypersensitivity to semaglutide or any component of RYBELSUS®, or history of severe hypersensitivity reactions to Forxiga, such as anaphylaxis or angioedema.
- Taking medications affecting weight or energy intake/energy expenditure in the last 3 months, including weight loss medications, antipsychotic drugs or other medications as determined by the study physician
- Currently participating in weight loss programs or weight change in the past 3 months (\>5% current body weight)
- Women who are pregnant or plan to become pregnant
- Patients who cannot be followed for 3 years (due to a health situation or migration)
- Patients who are unwilling or unable to give informed consent
The study team makes the final eligibility decision.
Where it's taking place
- Zhunan, Miaoli County, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 24 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Zhunan, Miaoli County, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.