BridgeMD
New treatment option for Overweight
Official title Physical Inactivity and Appetite Regulation
ClinicalTrials.gov ID: NCT06240208
What this study is testing
- What it's testing
- The goal of this parallel-group, two-arm, assessor-blinded, randomised clinical trial is to investigate the effects of reducing physical activity on food intake and satiety in physically active and healthy males, 40-55 years of age. The main questions it aims to answer are: Does physical inactivity affect GLP-1 stimulated food intake?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 55, men only. Healthy volunteers may be eligible.
You may be able to join if
- Male
- Age ≥ 40 years and ≤ 55 years
- Body mass index (BMI) \> 20 and \< 25 kg/m2
- Physical activity level should as a minimum include: Active commuting by biking a minimum of 10 km, four days per week or an equivalent amount of...
- Healthy (based on self-reporting, pre-study medical examination and biochemical screening)
You likely can't join if
- Clinical or biochemical signs of disease
- HbA1c \> 39 mmol/mol
- Unable to allocate the needed time to fulfill the intervention
- Language barrier, mental incapacity, unwillingness, or inability to understand and be able to complete the interventions
See the full eligibility criteria
- Male
- Age ≥ 40 years and ≤ 55 years
- Body mass index (BMI) \> 20 and \< 25 kg/m2
- Physical activity level should as a minimum include: Active commuting by biking a minimum of 10 km, four days per week or an equivalent amount of other physical activity four days per week.
- Healthy (based on self-reporting, pre-study medical examination and biochemical screening)
- Can adhere to two weeks of inactivity (refrain from running, cycling and all other exercise while reducing steps to max. 1500 pr. day)
- Caucasian
- No change in body weight \> 5 kg within the last 6 months
- Eats breakfast and lunch daily
- Does not follow specific dietary restrictions
- No disliking of spaghetti bolognese
- No diagnosis of psychiatric disorder or treatment with anti-depressant or anti-psychotic medication
- No history of suicidal behavior or ideations.
- No previous surgical treatment for obesity
- No cardiovascular disease
- No rheumatologic disease
- No metabolic/endocrine disease
- No liver disease (ASAT or ALAT \>2x upper normal range)
- No other chronic disease
- No elite sports
- No frequent or chronic use of medications affecting bodyweight, physical performance, or inflammation (NSAIDS, DMARDS, corticosteroids)
- No current infection
- No history of cancer
- No anemia (hematocrit \<33%)
- No smoking
- No participation in other research intervention studies
- Clinical or biochemical signs of disease
- HbA1c \> 39 mmol/mol
- Unable to allocate the needed time to fulfill the intervention
- Language barrier, mental incapacity, unwillingness, or inability to understand and be able to complete the interventions
The study team makes the final eligibility decision.
Where it's taking place
- Copenhagen, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 40 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Copenhagen, Denmark. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.