BridgeMD
New treatment option for Pneumonia, Bacterial
Official title Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia
ClinicalTrials.gov ID: NCT06238297
What this study is testing
- What it's testing
- The current IDSA/ATS guidelines recommend Linezolid and Vancomycin for MRSA coverage in hospitalized patients with pneumonia, which is common clinical practice in Italy. However, a nasal PCR-assay for MRSA has a high negative predictive value and can facilitate rapid antibiotic de-escalation, thereby avoiding unnecessary anti-MRSA treatments.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- people 18 years or older.
- Patients hospitalized at the Azienda Consorziale Policlinico di Bari;
- Clinical diagnosis of CAP/HAP/VAP;
- Commitment by the prescribing physician to set an anti-MRSA antibiotic therapy in empirical
- Enrollement within 48h from the beginning of the empirical anti-MRSA therapy.
You likely can't join if
- Febrile neutropenia or severe immunodeficiency;
- Chronic airway infection (eg cystic fibrosis);
- Suspect of extrapulmonary infection by MRSA
- Refusal by the patient or legal guardian;
- Refusal by the physician in charge of the patient to perform antibiotic de-escalation based on the result of the nasal swab;
- Enrollment after 48 hours from the beginning of the empirical anti-MRSA therapy.
The study team makes the final eligibility decision.
Where it's taking place
- Bari, Italy
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bari, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.