BridgeMD
New treatment option for HIV Infections
Official title Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
ClinicalTrials.gov ID: NCT06226155
What this study is testing
- What it's testing
- The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV treatment adherence among people living with HIV in Zimbabwe. The new intervention, TENDAI4PrEP, will be designed to improve PrEP uptake and persistence among pregnant persons in Zimbabwe.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 15 to 55
You may be able to join if
- Across all aims participants must be
- Pregnant
- Presenting at the Chitungwiza Central Hospital ANC
- Aged 15+
- Willing to provide informed consent or assent
You likely can't join if
- Inability to provide informed consent/assent and/or complete procedures in Shona or English
- Current interfering untreated or unstable mental health condition that precludes functional involvement in the study (e.g., active psychosis...
See the full eligibility criteria
- Across all aims participants must be
- Pregnant
- Presenting at the Chitungwiza Central Hospital ANC
- Aged 15+
- Willing to provide informed consent or assent
- Have HIV negative status
- At risk for HIV acquisition (defined as having a male partner of unknown HIV status, suspicions of partner infidelity, reporting multiple partners, or history of STI and/or recent condomless sexual activity)
- Score \>5 on the Shona Symptom Questionnaire For the RCT, eligible participants must also be willing to
- Initiate PrEP prior to randomization
- Bring their pregnancy partner (if they are safe doing so).
- Inability to provide informed consent/assent and/or complete procedures in Shona or English
- Current interfering untreated or unstable mental health condition that precludes functional involvement in the study (e.g., active psychosis, untreated bipolar disorder)
The study team makes the final eligibility decision.
Where it's taking place
- Harare, Zimbabwe
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 15 years to 55 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Harare, Zimbabwe. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.