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Compares treatment options for Acne Vulgaris
Official title Weekly Isotretinoin vs Tetracycline for Moderate Acne
ClinicalTrials.gov ID: NCT06225570
What this study is testing
What is Isotretinoin?
Isotretinoin is an investigational medicine, given as an once-weekly pill taken by mouth, being studied as a potential treatment for acne vulgaris.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases.
- Phase 1: an early, usually small safety study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 and older. Healthy volunteers may be eligible.
You may be able to join if
- \- Male and Female patients, 12 years and older with a diagnosis of Moderate Acne Vulgaris
You likely can't join if
- Patients who are at baseline on long-term Tetracycline antibiotics, long-term Trimethoprim-Sulfamethoxazole, or on Spironolactone for any reason
- Patients who have taken Isotretinoin in the past 6 months
- Patients with hypersensitivity to Isotretinoin or to any of its components
- Females who are pregnant, likely to become pregnant, or will be breast-feeding during the study period
- Patients with a history of major depression, mania, or psychosis with an active episode during the past year including current psychotic symptoms...
- Adult patients with cognitive impairment
See the full eligibility criteria
- \- Male and Female patients, 12 years and older with a diagnosis of Moderate Acne Vulgaris
- Patients who are at baseline on long-term Tetracycline antibiotics, long-term Trimethoprim-Sulfamethoxazole, or on Spironolactone for any reason
- Patients who have taken Isotretinoin in the past 6 months
- Patients with hypersensitivity to Isotretinoin or to any of its components
- Females who are pregnant, likely to become pregnant, or will be breast-feeding during the study period
- Patients with a history of major depression, mania, or psychosis with an active episode during the past year including current psychotic symptoms and/or current suicidal ideation
- Adult patients with cognitive impairment
- Patients with baseline kidney or liver disease
- Patients with baseline hypertriglyceridemia
- Patients with history of or current pseudotumor cerebri
- Patients with any clinically significant unstable medical condition which could pose a risk to the safety of the patient
- Inability or unwillingness of subject or legal guardian/representative to give informed consent
The study team makes the final eligibility decision.
Where it's taking place
- Charleston, South Carolina, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Charleston, South Carolina, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.