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New treatment option for Septic Shock
Official title Xanthohumol as an Adjuvant in the Treatment of Septic Shock
ClinicalTrials.gov ID: NCT06225258
What this study is testing
- What it's testing
- Septic shock (SS) is a life-threatening condition resulting from excessive inflammatory response to bacterial, viral or/and fungal infections. It is associated with dysregulation of the immune system, activation of immune cells, and massive release of cytokines, commonly known as the cytokine storm (CS).
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- a septic shock in the early, acute phase,
- respiratory insufficiency required mechanical ventilation with PaO2/FiO2 \< 150,
- bacterial infection,
- procalcitonin higher than 5 ng/mL and interleukin 6 higher than 100 pg/mL,
- no allergy to hops or their derivatives,
You likely can't join if
- lack of agreement
- septic shock treated for more than 1 day,
- history of severe chronic cardiac, pulmonary and/or liver diseases
See the full eligibility criteria
- a septic shock in the early, acute phase,
- respiratory insufficiency required mechanical ventilation with PaO2/FiO2 \< 150,
- bacterial infection,
- procalcitonin higher than 5 ng/mL and interleukin 6 higher than 100 pg/mL,
- no allergy to hops or their derivatives,
- hemodynamic instability requiring vasopressor infusions
- lack of agreement
- septic shock treated for more than 1 day,
- history of severe chronic cardiac, pulmonary and/or liver diseases
The study team makes the final eligibility decision.
Where it's taking place
- Lublin, Lublin Voivodeship, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lublin, Lublin Voivodeship, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.