BridgeMD
Compares treatment options for Major Depressive Disorder
Official title A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
ClinicalTrials.gov ID: NCT06223880
What this study is testing
What is AXS-05?
AXS-05 is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for major depressive disorder.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse of depressive symptoms in subjects with major depressive disorder (MDD) who have responded to treatment with AXS-05.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Currently meets DSM-5 criteria for diagnosis of MDD without psychotic features
- Current major depressive episode of at least 4 weeks in duration
You likely can't join if
- Previously participated in another clinical study of AXS-05; received any investigational drug or device treatment within 30 days of (Screening)...
- Unable to comply with study procedures
- Medically inappropriate for study participation in the opinion of the investigator
The study team makes the final eligibility decision.
Where it's taking place
- Bellflower, California, United States
- Lafayette, California, United States
- Oceanside, California, United States
- Redlands, California, United States
- Riverside, California, United States
- San Diego, California, United States
- Upland, California, United States
- Brandon, Florida, United States
- Doral, Florida, United States
- Hialeah, Florida, United States
- Jacksonville, Florida, United States
- Miami, Florida, United States
- Orlando, Florida, United States
- Atlanta, Georgia, United States
- Chicago, Illinois, United States
- Overland Park, Kansas, United States
- New Orleans, Louisiana, United States
- Boston, Massachusetts, United States
- Saint Charles, Missouri, United States
- Las Vegas, Nevada, United States
+ 17 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bellflower, California, United States; Lafayette, California, United States; Oceanside, California, United States; Redlands, California, United States; Riverside, California, United States; San Diego, California, United States and 31 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.