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New treatment option for Cutaneous Melanoma
Official title EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
ClinicalTrials.gov ID: NCT06223659
What this study is testing
What is Eutectic Mixture of Local Anesthetics?
Eutectic Mixture of Local Anesthetics is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for cutaneous melanoma.
Also referred to as EMLA, Lidocaine-Prilocaine Eutectic Mixture.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This phase II trial tests how well EMLA topical cream works in treating pain in patients with skin cancers receiving Technetium 99 injections for a lymphoscintigraphy mapping procedure. A lymphoscintigraphy mapping procedure is used to find the main or lead lymph node (tissue that fight infection) so it can be removed and checked for tumor cells.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Biologic males or females
- 18 - 99 years of age
- Histologically confirmed cutaneous melanoma, Merkel cell carcinoma, squamous cell carcinoma, or other cutaneous malignancy for which...
You likely can't join if
- Known allergy or intolerance to EMLA cream, lidocaine, prilocaine, or any other local anesthetic
- History of adhesive allergy
- Contraindication to Tc99 injection for sentinel lymph node mapping
- Incarcerated patients
- Patients incapable of independently providing consent
- Mucosal or genital lymphoscintigraphy site
See the full eligibility criteria
- Biologic males or females
- 18 - 99 years of age
- Histologically confirmed cutaneous melanoma, Merkel cell carcinoma, squamous cell carcinoma, or other cutaneous malignancy for which lymphoscintigraphy and sentinel lymph node biopsy has been recommended.
- Known allergy or intolerance to EMLA cream, lidocaine, prilocaine, or any other local anesthetic
- History of adhesive allergy
- Contraindication to Tc99 injection for sentinel lymph node mapping
- Incarcerated patients
- Patients incapable of independently providing consent
- Mucosal or genital lymphoscintigraphy site
- Pregnancy
- Participant self-declared or Ohio State University (OSU) medical chart listing chronic pain as a pre-existing diagnosis
- Participants with chronic pain as defined by the Centers for Disease Control and Prevention (CDC):"pain lasting 3 months or more that can be caused by a disease or condition, injury, medical treatment, or unknown...
The study team makes the final eligibility decision.
Where it's taking place
- Columbus, Ohio, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Columbus, Ohio, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.