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New treatment option for Melasma
Official title Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration
ClinicalTrials.gov ID: NCT06221787
What this study is testing
- What it's testing
- Melasma is a refractory skin disease due to its complex pathogenesis and difficult treatment. Studies have found that human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) could serve as a novel cell-free therapeutic strategy in regenerative and aesthetic medicine.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- \- Patients diagnosed with chloasma who meet the clinical diagnostic standards and how well it works standards (revised version) of chloasma and have...
- It is hoped that exosomes combined with 1565 non-ablative fractional laser, blue aurora or micro-needle can improve facial chloasma.
- Fully understand and understand the content and significance of this study, implementation plan, possible benefits, risks and countermeasures, rights...
- Exclude post-inflammatory pigmentation, malar brown-green nevus, Riehl's melanosis, pigmented lichen planus and other skin diseases.
- people who agree not to use other cosmetic treatments related to the study during the study period.
You likely can't join if
- Patients who refuse to sign the informed consent form to participate in the trial;
- Those with a history of important organ diseases, or a history of autoimmune diseases or immune dysfunction;
- Abnormal coagulation function, current use of anticoagulants, thrombophilia and history of familial genetic diseases;
- Pregnant or lactating women;
- Patients taking oral contraceptives or hormone replacement therapy during the study period or within the past 12 months;
- Patients with scar constitution;
See the full eligibility criteria
- \- Patients diagnosed with chloasma who meet the clinical diagnostic standards and how well it works standards (revised version) of chloasma and have skin lesions on the face.
- It is hoped that exosomes combined with 1565 non-ablative fractional laser, blue aurora or micro-needle can improve facial chloasma.
- Fully understand and understand the content and significance of this study, implementation plan, possible benefits, risks and countermeasures, rights and obligations of people (including privacy protection, free...
- Exclude post-inflammatory pigmentation, malar brown-green nevus, Riehl's melanosis, pigmented lichen planus and other skin diseases.
- people who agree not to use other cosmetic treatments related to the study during the study period.
- Patients who refuse to sign the informed consent form to participate in the trial;
- Those with a history of important organ diseases, or a history of autoimmune diseases or immune dysfunction;
- Abnormal coagulation function, current use of anticoagulants, thrombophilia and history of familial genetic diseases;
- Pregnant or lactating women;
- Patients taking oral contraceptives or hormone replacement therapy during the study period or within the past 12 months;
- Patients with scar constitution;
- Active skin infection;
- Those who have a history of multiple severe allergies, a history of hereditary allergies, photosensitivity or photosensitivity drugs, such as sulfa drugs and tetracyclines, those who are allergic to local anesthetics...
- History of post-inflammatory pigmentation;
- Those who have received treatment for chloasma in the past;
- Those who have undergone chemical peeling, dermabrasion or other skin resurfacing on their face in the past;
- Patients who are participating in other clinical studies;
- Other reasons that the researcher considers unsuitable for clinical investigators.
The study team makes the final eligibility decision.
Where it's taking place
- Fuzhou, Fujian, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Fuzhou, Fujian, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.