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New treatment option for Cervical Intraepithelial Neoplasia-II
Official title Effect of Honey For CIN II
ClinicalTrials.gov ID: NCT06219018
What this study is testing
What is Medical grade honey formulation (MGH) (L-Mesitran®)?
Medical grade honey formulation (MGH) (L-Mesitran®) is an investigational medicine, given as an once-weekly, being studied as a potential treatment for cervical intraepithelial neoplasia-ii.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The following hypothesis is tested: Medical grade honey in CIN II causes a higher clearance of the hr-HPV virus and an increase in the normalization of CIN II lesions compared to expectant management.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40, women only. Healthy volunteers may be eligible.
You may be able to join if
- Women 18-40 years
- Primary CIN II confirmed histologically in the biopsy on colposcopic examination
- Sufficient mastery of the Dutch language
You likely can't join if
- Simultaneous abnormality in columnar epithelial cells (AIS).
- Hr-HPV negative cytology
- Immunosuppressant use/Autoimmune disease (HIV, CVID)
- History of cervical carcinoma or previous treatment for CIN (LLETZ or imiquimod)
- Pregnancy or the intention to become pregnant during the study period
- Legal incompetence
See the full eligibility criteria
- Women 18-40 years
- Primary CIN II confirmed histologically in the biopsy on colposcopic examination
- Sufficient mastery of the Dutch language
- Simultaneous abnormality in columnar epithelial cells (AIS).
- Hr-HPV negative cytology
- Immunosuppressant use/Autoimmune disease (HIV, CVID)
- History of cervical carcinoma or previous treatment for CIN (LLETZ or imiquimod)
- Pregnancy or the intention to become pregnant during the study period
- Legal incompetence
- Known allergies to honey
The study team makes the final eligibility decision.
Where it's taking place
- Heerlen, Limburg, Netherlands
- Maastricht, Limburg, Netherlands
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Heerlen, Limburg, Netherlands; Maastricht, Limburg, Netherlands. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.