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Compares treatment options for Coronary Artery Disease
Official title FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With Coronary Artery Disease
ClinicalTrials.gov ID: NCT06218485
What this study is testing
- What it's testing
- To compare the clinical outcomes of fractional flow reserve (FFR)-guided strategy versus intravascular ultrasound (IVUS)-guided stent implantation after angiography-derived FFR-based decision-making.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 and older
You may be able to join if
- Subject must be ≥ 19 years.
- Subject is able to verbally confirm understanding of risks, benefits and treatment alternatives of receiving invasive physiologic or imaging...
- people suspected with ischemic heart disease.
- people with coronary artery diameter stenosis 50-90% by angiography-based visual estimation eligible for stent implantation.
- Target vessel size ≥ 2.5mm in visual estimation.
You likely can't join if
- Known hypersensitivity or contraindication to any of the following medications: Heparin, Aspirin, Clopidogrel, Prasugrel, Ticagrelor
- Active pathologic bleeding.
- Gastrointestinal or genitourinary major bleeding within the prior 3 months.
- History of bleeding diathesis, known coagulopathy.
- Non-cardiac co-morbid conditions with life expectancy \< 2 years.
- Target lesion located in coronary arterial bypass graft.
See the full eligibility criteria
- Subject must be ≥ 19 years.
- Subject is able to verbally confirm understanding of risks, benefits and treatment alternatives of receiving invasive physiologic or imaging evaluation and PCI with a drug-eluting stent (DES) and he/she or his/her...
- people suspected with ischemic heart disease.
- people with coronary artery diameter stenosis 50-90% by angiography-based visual estimation eligible for stent implantation.
- Target vessel size ≥ 2.5mm in visual estimation.
- Known hypersensitivity or contraindication to any of the following medications: Heparin, Aspirin, Clopidogrel, Prasugrel, Ticagrelor
- Active pathologic bleeding.
- Gastrointestinal or genitourinary major bleeding within the prior 3 months.
- History of bleeding diathesis, known coagulopathy.
- Non-cardiac co-morbid conditions with life expectancy \< 2 years.
- Target lesion located in coronary arterial bypass graft.
- Left main coronary artery stenosis ≥ 50%.
- Chronic total occlusion in the study target vessel.
- Culprit lesion of ST-elevation myocardial infarction (STEMI).
- Not eligible for angiography-derived FFR (ostial RCA ≥ 50% stenosis, severe tortuosity, severe overlap, poor image quality).
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
- Guangdong, China
- Hangzhou, China
- Huzhou, China
- Jinan, China
- Jinhua, China
- Kunming, China
- Nanchang, China
- Ningbo, China
- Shanghai, China
- Wenzhou, China
- Bucheon-si, South Korea
- Busan, South Korea
- Daegu, South Korea
- Donggu, South Korea
- Goyang, South Korea
- Seoul, South Korea
- Uijeongbu-si, South Korea
- Ulsan, South Korea
- Wŏnju, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China; Guangdong, China; Hangzhou, China; Huzhou, China; Jinan, China; Jinhua, China and 14 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.