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New treatment option for Autism Spectrum Disorder
Official title Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)
ClinicalTrials.gov ID: NCT06214065
What this study is testing
- What it's testing
- The goal of this observational study is to test the modulation effect of different transcranial magnetic stimulation (TMS) on the neural network supporting our ability to create mental representations of others (also known as mentalizing) in young adults with autism. The main question it aims to answers is can stimulation of the right temporoparietal junction can change brain activity related to mentalizing during social interaction in the stimulation area and other brain areas connected to it.
- This is a blinded study.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35. Healthy volunteers may be eligible.
You may be able to join if
- Estimated full-scale IQ\>80
- Right handed
- Fluent in English
- Individual can cooperate with all study's procedures
- No history of neurological disorder (e.g. epilepsy) or neurosurgery
See the full eligibility criteria
- Estimated full-scale IQ\>80
- Right handed
- Fluent in English
- Individual can cooperate with all study's procedures
- No history of neurological disorder (e.g. epilepsy) or neurosurgery
- No major medical condition (e.g. cancer, heart failure)
- No history of significant head injury
- No primary relatives with history of any neurological disorder with a potentially hereditary basis, including epilepsy or MS
- No current use of medications with psychotropic (e.g., benzodiazepines) or anti- or pro-convulsants
- No current substance use (determined by urine screen and breathalyzer in all visits)
- Negative urine pregnancy (women) test at time of MRI scans
- No MR contra-indications (e.g. in-body metal implant, severe claustrophobia)
- No previous participation in our lab in a study including the Domino fMRI task
- For ASD: Stable medication treatment 4 weeks prior to study enrollment
- For Control Group: No current or history of psychiatric disorders, other than simple phobia, and/or primary relatives with ASD
The study team makes the final eligibility decision.
Where it's taking place
- Hartford, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 35 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hartford, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.