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New treatment option for Drug-resistant Neuropathic Pain
Official title Non-invasive Personalized Transcranial Cortical Neurostimulation for Pain Relief
ClinicalTrials.gov ID: NCT06209645
What this study is testing
- What it's testing
- Neuropathic pain is a public health problem with less than 50% of patients being relieved by drug treatments. Surgically implanted motor cortex stimulation represents an invasive therapeutic solution capable of relieving a significant proportion of drug-resistant patients (1 in 2); it cannot, however, be offered to all patients, and is not morbidity-free.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Aged 18 to 80 years
- Neuropathic pain of more than one year's duration1
- Failed treatment with tricyclic or tetracyclic antidepressants, antiepileptics and a combination of morphine and a serotonin (5HT) norepinephrine...
- Average pain intensity of at least 4/10 in the month preceding the inclusion visit.
- Recipient or beneficiary of a social security scheme-
You likely can't join if
- Chronic non-neuropathic pain or pain associated with progressive pathology, active epilepsy, unhealed scalp wound, impaired comprehension or...
- Active epilepsy, treated or not
- Unhealed scalp wound adjacent to EEG recording electrodes or transcranial stimulation application (contraindication to Medical Device (DM) use)
- Pregnant or breast-feeding women
- Inability to understand or follow the ins and outs of the study, in particular the need to assess pain intensity on a daily basis or to trace it...
- People under guardianship, curatorship or legal protection
See the full eligibility criteria
- Aged 18 to 80 years
- Neuropathic pain of more than one year's duration1
- Failed treatment with tricyclic or tetracyclic antidepressants, antiepileptics and a combination of morphine and a serotonin (5HT) norepinephrine (NA2) reuptake inhibitor, in the absence of contraindication.
- Average pain intensity of at least 4/10 in the month preceding the inclusion visit.
- Recipient or beneficiary of a social security scheme-
- Chronic non-neuropathic pain or pain associated with progressive pathology, active epilepsy, unhealed scalp wound, impaired comprehension or communication that prevents subjective daily and weekly assessments.
- Active epilepsy, treated or not
- Unhealed scalp wound adjacent to EEG recording electrodes or transcranial stimulation application (contraindication to Medical Device (DM) use)
- Pregnant or breast-feeding women
- Inability to understand or follow the ins and outs of the study, in particular the need to assess pain intensity on a daily basis or to trace it, possibly with the help of a third party (comprehension or communication...
- People under guardianship, curatorship or legal protection
- Persons deprived of their liberty, persons under psychiatric care and persons admitted to a health or social establishment for purposes other than clinical investigation
- Participation in other research interfering with the present study.
The study team makes the final eligibility decision.
Where it's taking place
- Bron, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bron, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.