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Tests treatment safety and results for Fecal Microbiota Transplantation
Official title Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Reducing Recurrence of Colorectal Adenoma (CRA)
ClinicalTrials.gov ID: NCT06205862
What this study is testing
- What it's testing
- The goal of this clinical trial is to learn about the efficacy and safety of fecal microbiota transplantation in reducing recurrence of colorectal adenomas after endoscopic resection. The main questions it aims to answer are: the efficacy and safety of fecal microbiota transplantation in reducing the recurrence rate of colorectal adenomas after endoscopic resection.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Age 18-75, gender not specified.
- Colorectal adenoma patients diagnosed by colonoscopy and treated with endoscopic resection (such as EMR, ESD, APC treatment, etc.)，or patients who...
- Individuals who are able to swallow pills/capsules.
- Individuals who voluntarily sign an informed consent form after fully understanding the purpose and procedures of this study, the characteristics of...
You likely can't join if
- Individuals in whom the adenoma was not completely removed in a previous colonoscopy;
- Individuals who experienced serious complications during or after adenoma resection, including perforation, uncontrollable bleeding, or severe...
- Individuals with a history of familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer (HNPCC/Lynch syndrome);
- Individuals regularly taking aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase 2 (COX2) inhibitors, calcium, or vitamin D;
- Individuals with a history of subtotal or total gastrectomy or partial bowel resection;
- People who cannot tolerate colonoscopy;
See the full eligibility criteria
- Age 18-75, gender not specified.
- Colorectal adenoma patients diagnosed by colonoscopy and treated with endoscopic resection (such as EMR, ESD, APC treatment, etc.)，or patients who have undergone endoscopic resection within the past 6 months and have...
- Individuals who are able to swallow pills/capsules.
- Individuals who voluntarily sign an informed consent form after fully understanding the purpose and procedures of this study, the characteristics of the disease, the therapeutic how well it works of the drugs, the...
- Individuals in whom the adenoma was not completely removed in a previous colonoscopy;
- Individuals who experienced serious complications during or after adenoma resection, including perforation, uncontrollable bleeding, or severe infection;
- Individuals with a history of familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer (HNPCC/Lynch syndrome);
- Individuals regularly taking aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase 2 (COX2) inhibitors, calcium, or vitamin D;
- Individuals with a history of subtotal or total gastrectomy or partial bowel resection;
- People who cannot tolerate colonoscopy;
- Individuals with allergic diathesis, known allergies to fecal microbiota transplantation, drug allergies, or intolerance;
- Individuals with serious heart, liver, or kidney diseases, or any history of cancer;
- People suffering from severe constipation;
- Pregnant women, breastfeeding mothers, or women planning to become pregnant;
- Patients with mental illness who are unable to cooperate;
- Individuals involved in the design, planning, or execution of this trial;
- Any other individuals who, in the investigator's opinion, are unsuitable for inclusion.
The study team makes the final eligibility decision.
Where it's taking place
- Guangzhou, Guangdong, China
- Shenzhen, Guangdong, China
- Shunde, Guangdong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guangzhou, Guangdong, China; Shenzhen, Guangdong, China; Shunde, Guangdong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.