BridgeMD
New treatment option for Cardiac Arrest
Official title The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA
ClinicalTrials.gov ID: NCT06203847
What this study is testing
What is Combination group?
Combination group is an investigational medicine, being studied as a potential treatment for cardiac arrest.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This project is a randomized controlled clinical research design, The hypothesis P-I-C-O of the study is: For adult patients in the Taipei City and New Taipei City communities who have suffered sudden non-traumatic death and have been resuscitated by advanced paramedics, the intervention group that receives combined drug treatment (epinephrine, vasopressin, methylprednisolone) has a better rate of sustained recovery of spontaneous circulation (ROSC) (primary outcome) and long-term survival status (secondary outcomes) compared to the control group that receives single drug treatment (epinephrine).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients (aged \>= 18 )
- Out-of-hospital cardiac arrest in the studied regions
- Treated by paramedics authorized and capable of giving prehospital medication
You likely can't join if
- OHCA with traumatic etiology
- Obvious signs of death like decapitation, rigor mortis, livor mortis, decomposition, etc.
- DNR (Do Not Resuscitation) or termination of resuscitation requested by the family
- Patients with known or suspected pregnancy
- No vascular access was established before hospital arrival
- ROSC before the administrated medication
See the full eligibility criteria
- Adult patients (aged \>= 18 )
- Out-of-hospital cardiac arrest in the studied regions
- Treated by paramedics authorized and capable of giving prehospital medication
- OHCA with traumatic etiology
- Obvious signs of death like decapitation, rigor mortis, livor mortis, decomposition, etc.
- DNR (Do Not Resuscitation) or termination of resuscitation requested by the family
- Patients with known or suspected pregnancy
- No vascular access was established before hospital arrival
- ROSC before the administrated medication
- No patient contact (cancelled ambulance call or the patient was transported to the hospital before the arrival of trial-trained paramedics)
- Received epinephrine prior to the arrival of trial-trained paramedics
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.