Recruiting PHASE2, PHASE3 Endodontic Disease

New treatment option for Endodontic Disease

Official title Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication

ClinicalTrials.gov ID: NCT06196515

What this study is testing

What is Calcium hydroxide?

Calcium hydroxide is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for endodontic disease.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The aim of the study is to evaluate the anti-bacterial potential of Nano Calcium Hydroxide as an intracanal medication in primary endodontic treatment of permanent molars.
  • Phase 3: a large, late-stage study

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 21 to 49. Healthy volunteers may be eligible.

You may be able to join if

  • healthy males and females.
  • age range between 21-49.
  • patients with no physical disability or psychological problems.
  • patients presenting with single permanent molar with signs and/or symptoms of apical periodontitis, and having Periapican index ≥ 2.

You likely can't join if

  • pregnant women.
  • patients with immune-compromised disease.
  • patients with complicated systemic diseases.
  • patients who took antibiotics within a period of 1 month.
  • patients with known sensitivity to the medicaments or pharmaceuticals used in this study.
  • Non-restorable teeth including root fractures, and/or advanced periodontal involvement.

The study team makes the final eligibility decision.

Where it's taking place

  • Cairo, Egypt

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 21 years to 49 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Cairo, Egypt. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.