Recruiting NA Glioblastoma

New treatment option for Glioblastoma

Official title Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of Glioblastoma

ClinicalTrials.gov ID: NCT06183983

What this study is testing

What it's testing
The goal of this prospective cohort study is to assess the potential of advanced MRI for improved radiotherapy target delineation in patients diagnosed with glioblastoma. The main questions it aims to answer are: How does the coverage of the recurrence volume by a radiotherapy plan based on advanced MRI compare to the coverage by the clinical radiotherapy plan?

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older

You may be able to join if

  • Written informed consent;
  • Adult (18 years or older);
  • Diagnosed with IDH-wildtype glioblastoma, as confirmed by pathology including molecular analysis post resection/biopsy;
  • Referred to the outpatient clinic of the Dept. of Radiotherapy to undergo standard treatment with radiotherapy (30x2 Gy or 15x2.67Gy or 10x3.4Gy).

You likely can't join if

  • Contraindication for (3 Tesla) MRI;
  • Contraindication for use of gadolinium-based contrast agent (e.g. subject having renal deficiency or known allergy);
  • Referred for treatment of recurrent glioblastoma;
  • Previous radiotherapy to the brain;
  • Unable to give informed consent

The study team makes the final eligibility decision.

Where it's taking place

  • Rotterdam, South Holland, Netherlands

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Rotterdam, South Holland, Netherlands. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.