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New treatment option for Metabolic Syndrome
Official title Effects of Cetoleic Acid on Atherosclerosis (Ketolinsyre's Effekt på Aterosklerose)
ClinicalTrials.gov ID: NCT06172335
What this study is testing
- What it's testing
- In this Randomized Controlled Trial (RCT) we want to study the effect of an oil with high concentrations of cetoelic acid (C22:n1-11) (intervention) compared to supplements with a low concentration of cetoleic acid (control), but with equivalent content of EPA og DHA, on plasma levels of epa and dha as well as atherosclerotic markers, glucose, c-peptide and triglycerides in a patient group with a metabolically unfavorable phenotype. Our primary endpoints are changes in the concentration of EPA and DHA in plasma.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 70
You may be able to join if
- Triglycerides \> 1.7 mmol/L
- Waist measurement \> 80 cm (women) and \> 94 cm (men)
You likely can't join if
- Chronic disease (liver/kidney/metabolism)
- Ongoing active cancer treatment
- Excessive alcohol consumption (\>40g/day)
- Pregnant/breastfeeding or planned pregnancy during the intervention
- High intake of fish (\>3 weekly meals)
- Level of free thyroxine (T4) and triiodothyronine (T3) outside reference ranges.
See the full eligibility criteria
- Triglycerides \> 1.7 mmol/L
- Waist measurement \> 80 cm (women) and \> 94 cm (men)
- Chronic disease (liver/kidney/metabolism)
- Ongoing active cancer treatment
- Excessive alcohol consumption (\>40g/day)
- Pregnant/breastfeeding or planned pregnancy during the intervention
- High intake of fish (\>3 weekly meals)
- Level of free thyroxine (T4) and triiodothyronine (T3) outside reference ranges.
- Hypertension (≥ 160/ 100 mmHg)
- Total cholesterol \> 7.8 mmol/L
- Blood donation during the intervention period
- Difficulty following the protocol
- Smoking or sniffing
- Regular use (\> 1 day/week) of anti-inflammatory drugs
- Regular use of omega-3 supplements/cod liver oil
- Drug use other than stable use of statins, hypertension drugs (Ca antagonists, diuretics and beta blockers).
- Hormonal treatment excluding stable use of thyroxine and birth control pills/contraceptive rod
The study team makes the final eligibility decision.
Where it's taking place
- Oslo, Norway
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Oslo, Norway. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.