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New treatment option for Staphylococcus Aureus Bacteremia
Official title Evaluating Simplified Layered Consent for Clinical Trials
ClinicalTrials.gov ID: NCT06168474
What this study is testing
- What it's testing
- The goal of this clinical trial (the SIMPLY-SNAP trial) is to compare a simplified layered consent form to a full-length consent form for use during the informed consent process for a larger clinical trial of treatment of Staphylococcus aureus bloodstream infection (the SNAP trial). The main questions it aims to answer are: Does use of a simplified layered consent form lead to an increased recruitment rate to the SNAP trial?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- All from the larger SNAP trial:
- S. aureus complex grown from ≥1 blood culture
- Admitted to a participating hospital at the time of eligibility assessment
- Specific additional for SIMPLY-SNAP:
- Admitted to participating hospital of SIMPLY-SNAP
You likely can't join if
- All exclusion criteria from larger SNAP trial:
- Time of anticipated platform entry is greater than 72 hours post collection of the index blood culture
- Polymicrobial bacteremia, defined as more than one organism in the index blood cultures, excluding those organisms judged to be contaminants by...
- Patient currently being treated with a systemic antibacterial agent that cannot be ceased
- Known previous participation in SNAP
- Known positive blood culture for S. aureus between 72 hours and 180 days prior to the time of eligibility assessment
See the full eligibility criteria
- All from the larger SNAP trial:
- S. aureus complex grown from ≥1 blood culture
- Admitted to a participating hospital at the time of eligibility assessment
- Specific additional for SIMPLY-SNAP:
- Admitted to participating hospital of SIMPLY-SNAP
- Self-reported proficiency in English or French adequate to be able to participate in consent process carried out solely in English or French (as the supplementary consent materials required in the simplified consent...
- All exclusion criteria from larger SNAP trial:
- Time of anticipated platform entry is greater than 72 hours post collection of the index blood culture
- Polymicrobial bacteremia, defined as more than one organism in the index blood cultures, excluding those organisms judged to be contaminants by either the microbiology laboratory or treating clinician
- Patient currently being treated with a systemic antibacterial agent that cannot be ceased
- Known previous participation in SNAP
- Known positive blood culture for S. aureus between 72 hours and 180 days prior to the time of eligibility assessment
- Treating team deems enrolment in the study is not in the best interest of the patient
- Treating team believes that death is imminent and inevitable
- Patient is for end-of-life care and antibiotic treatment is considered inappropriate
- Patient \<18 years of age and paediatric recruitment not approved at recruiting site
- Specific additional exclusion criteria for SIMPLY-SNAP: None
The study team makes the final eligibility decision.
Where it's taking place
- Calgary, Alberta, Canada
- Hamilton, Ontario, Canada
- Ottawa, Ontario, Canada
- Toronto, Ontario, Canada
- Montreal, Quebec, Canada
- Québec, Quebec, Canada
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Calgary, Alberta, Canada; Hamilton, Ontario, Canada; Ottawa, Ontario, Canada; Toronto, Ontario, Canada; Montreal, Quebec, Canada; Québec, Quebec, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.