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New treatment option for Lupus Erythematosus, Systemic
Official title Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
ClinicalTrials.gov ID: NCT06166199
What this study is testing
- What it's testing
- The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- ≥18 years old
- Fulfilment of the 1982 American College of Rheumatology (ACR) criteria; or 2012 Systemic Lupus International Collaborating Clinics (SLICC/ACR-Damage...
- Low to moderate disease activity, for example defined as a score of ≤5 in the clinical version of the SLE Disease Activity Index 2000 (SLEDAI-2K)...
- Low/minimal or no organ damage, for example defined as a score of ≤3 in the SLICC/ACR DI
- Stable pharmacological treatment
You likely can't join if
- Symptoms or signs of cerebro-vascular disease, pulmonary embolus, pulmonary hypertension, pulmonary fibrosis, cardiovascular disease, angina...
- Patients who fulfil the absolute contraindications for maximal exercise testing according to American Heart Association
- Patients who cannot perform a maximal ergometercycle exercise test due to the disease
- Diseases or other conditions that strongly reduce the ability to exercise or that exercise is not recommended
- Patients who perform regular aerobic fitness training and muscle strength exercise sessions at fixed times, \>1 time/week
- Pregnancy
See the full eligibility criteria
- ≥18 years old
- Fulfilment of the 1982 American College of Rheumatology (ACR) criteria; or 2012 Systemic Lupus International Collaborating Clinics (SLICC/ACR-Damage Index (DI)) classification criteria; or EULAR/ACR criteria; or...
- Low to moderate disease activity, for example defined as a score of ≤5 in the clinical version of the SLE Disease Activity Index 2000 (SLEDAI-2K), i.e., excluding the serological descriptors (anti-dsDNA positivity and...
- Low/minimal or no organ damage, for example defined as a score of ≤3 in the SLICC/ACR DI
- Stable pharmacological treatment
- The ability to perform a maximal ergometercycle exercise test
- Be able to read and understand Swedish
- Symptoms or signs of cerebro-vascular disease, pulmonary embolus, pulmonary hypertension, pulmonary fibrosis, cardiovascular disease, angina pectoris, myocardial infarction, dyspnea at rest, uncontrolled blood pressure...
- Patients who fulfil the absolute contraindications for maximal exercise testing according to American Heart Association
- Patients who cannot perform a maximal ergometercycle exercise test due to the disease
- Diseases or other conditions that strongly reduce the ability to exercise or that exercise is not recommended
- Patients who perform regular aerobic fitness training and muscle strength exercise sessions at fixed times, \>1 time/week
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Stockholm, Huddinge, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Stockholm, Huddinge, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.