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New treatment option for Dry Age-related Macular Degeneration
Official title Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study
ClinicalTrials.gov ID: NCT06165068
What this study is testing
What is Aspirin 81Mg Ec Tab?
Aspirin 81Mg Ec Tab is an investigational medicine, being studied as a potential treatment for dry age-related macular degeneration.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this clinical trial is to evaluate the effect of low doses of antiplatelet medications (aspirin 81 mg/day or clopidogrel 75 mg/day) with or without a combination of antioxidants (N-acetylcysteine 600 mg/day) in a dry AMD patient with large drusen. Participants will divided in to three groups.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 85
You may be able to join if
- Dry AMD with at least 1 large drusen. According to the AREDS study, large drusen have a size of more than 125 micron.
- Patients can evaluate SD-OCT (Spectral domain optical coherence tomography), OCT angiography, and best-corrected visual acuity.
- Age range: 50-85 years
- Patients who have previously used antiplatelet drugs.
You likely can't join if
- Patient with advanced AMD, such as geographic atrophy, neovascular complications (choroidal neovascularization)
- Patient with additional retinal diseases that affect visual acuity, e.g., retinal detachment, diabetic macular edema.
- Patient with a history of intravitreal anti-VEGF injection or macular laser.
- Patient using SSRIs, SNRIs, azole, NSAIDs, dual antiplatelet, anticoagulant medications.
The study team makes the final eligibility decision.
Where it's taking place
- Bangkok, Dusit, Thailand
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bangkok, Dusit, Thailand. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.