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New treatment option for Histamine
Official title The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
ClinicalTrials.gov ID: NCT06152497
What this study is testing
What is H1 blockade: Telfast: 180mg Fexofenadine?
H1 blockade: Telfast: 180mg Fexofenadine is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for histamine.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, men only. Healthy volunteers may be eligible.
You may be able to join if
- Male
- 18-45 years
- Not to medium physically active
You likely can't join if
- Smoking
- Chronic disease
- High blood pressure
- Supplement or medication intake
- Seasonal allergies
- Vegetarian / vegan
See the full eligibility criteria
- Male
- 18-45 years
- Not to medium physically active
- Smoking
- Chronic disease
- High blood pressure
- Supplement or medication intake
- Seasonal allergies
- Vegetarian / vegan
- Resistance trained
The study team makes the final eligibility decision.
Where it's taking place
- Ghent, Oost-Vlaanderen, Belgium
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ghent, Oost-Vlaanderen, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.