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Tests treatment safety and results for Acute Kidney Injury
Official title Nafamostat Efficacy in Phase 3 Registrational CRRT Study
ClinicalTrials.gov ID: NCT06150742
What this study is testing
- What it's testing
- A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Patients requiring CRRT or undergoing CRRT initiated within the prior 48 hours
- Patients who cannot tolerate heparin or are at high risk of bleeding
You likely can't join if
- Patients weighing less than 50 kg
- Patients receiving systemic anticoagulation
- Patients with active bleeding
The study team makes the final eligibility decision.
Where it's taking place
- Los Angeles, California, United States
- Orlando, Florida, United States
- Detroit, Michigan, United States
- Albuquerque, New Mexico, United States
- Great Neck, New York, United States
- New York, New York, United States
- Cincinnati, Ohio, United States
- Pittsburgh, Pennsylvania, United States
- Charleston, South Carolina, United States
- Dallas, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Angeles, California, United States; Orlando, Florida, United States; Detroit, Michigan, United States; Albuquerque, New Mexico, United States; Great Neck, New York, United States; New York, New York, United States and 4 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.