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New treatment option for Parkinson Disease
Official title Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD
ClinicalTrials.gov ID: NCT06133283
What this study is testing
- What it's testing
- This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance, postural control and neuroplasticity (ability of brain to adapt in structure and function) in individuals with Parkinson's disease (PD). This study will utilize two groups - one group will receive the exercise and VR, while the other group will receive stretching exercise and VR over eight weeks.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Diagnosis of idiopathic PD (ages 18 -85) in Hoehn and Yahr stages 2 - 3.
- people need to demonstrate a score of equal to or greater than 23 on the Mini Mental State Examination.
- people who have a score of ≤21.5 on the Mini Balance Evaluations Systems Test (miniBESTest).
You likely can't join if
- people with a history of other neurological diseases (i.e., stroke, multiple sclerosis).
- people with a history of severe cardiopulmonary disease, uncontrolled hypertension, orthostatic hypotension, uncontrolled diabetes, severe...
- people with a history of PD-specific surgical procedures such as deep brain stimulation etc.
- people with a history of head injury.
- people with a history of seizures or epilepsy.
- people who are currently pregnant.
See the full eligibility criteria
- Diagnosis of idiopathic PD (ages 18 -85) in Hoehn and Yahr stages 2 - 3.
- people need to demonstrate a score of equal to or greater than 23 on the Mini Mental State Examination.
- people who have a score of ≤21.5 on the Mini Balance Evaluations Systems Test (miniBESTest).
- people with a history of other neurological diseases (i.e., stroke, multiple sclerosis).
- people with a history of severe cardiopulmonary disease, uncontrolled hypertension, orthostatic hypotension, uncontrolled diabetes, severe osteoporosis, severe arthritis affecting their lower extremity joints.
- people with a history of PD-specific surgical procedures such as deep brain stimulation etc.
- people with a history of head injury.
- people with a history of seizures or epilepsy.
- people who are currently pregnant.
- Individuals who use of medications that could alter corticomotor excitability or increase risk of seizure.
- Individuals with skull abnormalities, fractures or unexplained, recurring headaches.
The study team makes the final eligibility decision.
Where it's taking place
- San Antonio, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include San Antonio, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.