BridgeMD
New treatment option for Cerebral Stroke
Official title Super-Resolution Ultrasound of the Brain in 3D
ClinicalTrials.gov ID: NCT06133179
What this study is testing
- What it's testing
- The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an off-line analysis by 3D ultrasound localization microscopy. Visualization of these vessels would allow us to conclude on the presence, or absence, of an ischemic stroke in the region of the middle cerebral artery.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patient aged 18 and over
- Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery
- Patient with lesion observable on MRI
- Patient included between 24 hours and 7 days after the ischemic stroke
- Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery
You likely can't join if
- Contralateral middle cerebral artery territory stroke or contralateral middle cerebral artery occlusion
- Patient with contraindication to Doppler ultrasound with contrast (right-left shunt, severe pulmonary arterial hypertension)
- Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride) or these excipients
- Patient with uncontrolled systemic hypertension
- Patient with respiratory distress syndrome
- Patient under guardianship or curatorship
See the full eligibility criteria
- Patient aged 18 and over
- Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery
- Patient with lesion observable on MRI
- Patient included between 24 hours and 7 days after the ischemic stroke
- Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery
- Patient having signed free, informed and written consent
- Patient affiliated to a social security system (excluding AME)
- Contralateral middle cerebral artery territory stroke or contralateral middle cerebral artery occlusion
- Patient with contraindication to Doppler ultrasound with contrast (right-left shunt, severe pulmonary arterial hypertension)
- Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride) or these excipients
- Patient with uncontrolled systemic hypertension
- Patient with respiratory distress syndrome
- Patient under guardianship or curatorship
- Pregnant or breastfeeding patient (positive blood pregnancy test during hospitalization)
- Patient with damaged skin at the temporal level
- Patient having presented in the 7 days preceding inclusion an acute coronary syndrome or suffering from unstable ischemic heart disease
The study team makes the final eligibility decision.
Where it's taking place
- Paris, Île-de-France Region, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Paris, Île-de-France Region, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.