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New treatment option for Vision Loss Partial
Official title Effect of Visual Retraining After Stroke
ClinicalTrials.gov ID: NCT06121219
What this study is testing
- What it's testing
- This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intensive visual retraining on the residual visual system, processing of visual information and the use of such information in real-world situations following damage.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 80. Healthy volunteers may be eligible.
You may be able to join if
- Cortically Blind people Inclusion:
- Between 21 and 80 years of age
- Residents of the United States or Canada
- Unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range...
- Reliable visual field defects in both eyes as measured by Humphrey, MAIA, Goldmann, and/or equivalent perimetry, large enough to enclose a 5-deg...
See the full eligibility criteria
- Cortically Blind people Inclusion:
- Between 21 and 80 years of age
- Residents of the United States or Canada
- Unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range (21-75 years)
- Reliable visual field defects in both eyes as measured by Humphrey, MAIA, Goldmann, and/or equivalent perimetry, large enough to enclose a 5-deg diameter visual stimulus.
- Able to fixate on visual targets reliably for 1000ms
- Must have a home computer (desktop or laptop) and reliable internet access
- Willing, able, and competent to provide informed consent
- Normal cognitive abilities, able to understand written and oral instructions in English, and competent and responsible adults in order to complete the visual training at home, independently, as instructed, for several...
- Past or present eye disease interfering with visual acuity
- BCVA worse than 20/40 in either eye
- Damage to the dorsal Lateral Geniculate Nucleus
- Diffuse whole brain degenerative processes
- History of traumatic brain injury
- Any other brain damage deemed by study staff to potentially interfere with training ability or outcome measures
- Documented history of drug/alcohol abuse
- Currently taking neuroactive medications which would impact training, as determined by PI
- Presence of cognitive or seizure disorders
- One-sided attentional neglect
- people who lack the competence or are otherwise unable to perform the visual training exercises as directed. Control people (n = 50) Inclusion:
- Between 21 and 80 years of age
- Report no history of neurological disorder.
- Competent and responsible, as determined by the Principal Investigator. Exclusion:
- Presence of damage to the visual system
- Presence of an active disease process involving their nervous system.
- Cognitive or seizure disorders
- Best corrected visual acuity worse than 20/40 in either eye
- Presence of vision field loss from ocular disease or disorder
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.