BridgeMD
New treatment option for Smoking Addiction
Official title Addictive Threshold of Nicotine
ClinicalTrials.gov ID: NCT06096714
What this study is testing
What is Nicotine?
Nicotine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for smoking addiction.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- To determine the nicotine threshold dose(s) for discrimination, subjective-rewarding effects, -and reinforcement in smokers with different levels of dependence.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 59
You may be able to join if
- to contact their primary care provider when necessary.
- Adults, aged 21 to 59 years. Individuals less than 21 will be excluded because the minimum age for purchasing tobacco products is 21 in our state...
- Smoking at least for one year and more frequently than once a week, smoking status confirmed with a semi-quantitative urine nicotine test. Smokers...
- In good health as verified by medical history, screening examination, and screening laboratory tests.
- For women, report using acceptable birth control methods.
You likely can't join if
- History of major medical or psychiatric disorders that the physician investigator deems as contraindicated for the participant to be in the study
- regular current use of certain psychotropic medications (such as mood stabilizers, antipsychotics, or anxiolytics being prescribed to treat bipolar...
- current untreated alcohol or substance use disorder for any other recreational or prescription drugs other than nicotine
- for women, pregnant as determined by pregnancy screening, or breastfeeding
- seeking (or undergoing) treatment for tobacco dependence or smoking.
The study team makes the final eligibility decision.
Where it's taking place
- West Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 59 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include West Haven, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.