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New treatment option for Coronary Artery Disease
Official title Effects of Cangrelor on MIcRovAscular Disfunction During Elective Percutaneous CORonary Intervention
ClinicalTrials.gov ID: NCT06089577
What this study is testing
What is Cangrelor 50 MG?
Cangrelor 50 MG is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for coronary artery disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Dual Antiplatelet Therapy represents the main therapy for patients presenting with chronic coronary syndromes and undergoing elective PCI. However, most of these patients are not properly covered in terms of inhibition of platelets aggregation at the time of PCI, and are exposed to an higher risk of microvascular damage which in turns might be responsible of residual symptoms persistence and the findings of residual ischemia at the non-invasive tests.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients;
- Signed Informed Consent;
- Chronic coronary syndromes;
- P2Y12-inhibitors naive patients;
- Elective PCI of a functionally significant (FFR ≤ 0.80) de-novo intermediate coronary artery stenoses in a major vessel;
You likely can't join if
- Underaged patients;
- Acute Conorary Syndromes;
- Already on treatment with P2Y12-inhibitors;
- Heart failure with severe reduction of the left ventricle ejection fraction (LVEF \< 30%);
- Subtotal occlusion (diameter stenosis \> 90%) of the target lesion;
The study team makes the final eligibility decision.
Where it's taking place
- Ferrara, Italy
- Naples, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ferrara, Italy; Naples, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.