BridgeMD
New treatment option for Scoliosis Correction
Official title Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes
ClinicalTrials.gov ID: NCT06087510
What this study is testing
What is Esketamine?
Esketamine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for scoliosis correction.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Chronic postsurgical pain (CPSP) refers to pain that occurs or increases after surgery and lasts longer than 3 months. Severe acute postoperative pain is one of the major risk factors of CPSP.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients aged ≥18 years and body weight≥40 kg;
- Scheduled to undergo scoliosis correction with pedicle screw fixation;
- Required patient-controlled intravenous analgesia (PCIA) after surgery.
You likely can't join if
- Preoperative sick sinus syndrome, severe sinus bradycardia (heart rate \<50 beats per minute), atrioventricular block grade II or above without...
- Patients with moderate or severe obstructive sleep apnea diagnosed preoperatively or according to the STOP-Bang score;
- History of hyperthyroidism or pheochromocytoma;
- History of schizophrenia, epilepsy, myasthenia gravis;
- Severe liver dysfunction (Child-Pugh grade C), severe renal dysfunction (preoperative dialysis), or American Society of Anaesthesiologists grade ≥IV;
- Barrier in communication;
See the full eligibility criteria
- Patients aged ≥18 years and body weight≥40 kg;
- Scheduled to undergo scoliosis correction with pedicle screw fixation;
- Required patient-controlled intravenous analgesia (PCIA) after surgery.
- Preoperative sick sinus syndrome, severe sinus bradycardia (heart rate \<50 beats per minute), atrioventricular block grade II or above without pacemaker, congenital heart disease, arrhythmia, or other serious...
- Patients with moderate or severe obstructive sleep apnea diagnosed preoperatively or according to the STOP-Bang score;
- History of hyperthyroidism or pheochromocytoma;
- History of schizophrenia, epilepsy, myasthenia gravis;
- Severe liver dysfunction (Child-Pugh grade C), severe renal dysfunction (preoperative dialysis), or American Society of Anaesthesiologists grade ≥IV;
- Barrier in communication;
- Other conditions that were considered unsuitable for study participation.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, Beijing Municipality, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, Beijing Municipality, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.