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Official title Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
ClinicalTrials.gov ID: NCT06086873
What this study is testing
- What it's testing
- This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures for modSLA (SLActive, Institut Straumann AG, Switzerland) and NGA (TiUltraNP, Nobel Biocare AG, Switzerland) dental implants.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Age: over 18 years old,
- Gender: male and female.
- Patient must be able and willing to follow study procedures and instructions and have capacity to provide informed consent.
- Patient must require tooth extraction of a maxillary first premolar or single-rooted anterior tooth as the result of caries, endodontic failure or...
- The extraction site must have adjacent teeth present.
You likely can't join if
- Systemic disease that can interfere with dental implant therapy (e.g. uncontrolled diabetes)
- 2 adjacent teeth requiring extraction
- Greater than one wall of the socket missing - assessed at time of extraction
- Any contraindications for oral surgical procedures
- Any known systemic disease affecting bone metabolism (e.g. Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis, diabetes type I...
- Chronic treatment (i.e., 2 weeks or more) with any medication known to affect oral status (e.g., phenytoin, dihydropyridine, calcium antagonists and...
See the full eligibility criteria
- Age: over 18 years old,
- Gender: male and female.
- Patient must be able and willing to follow study procedures and instructions and have capacity to provide informed consent.
- Patient must require tooth extraction of a maxillary first premolar or single-rooted anterior tooth as the result of caries, endodontic failure or trauma
- The extraction site must have adjacent teeth present.
- Adjacent teeth with no evidence of interdental bone loss
- Systemic disease that can interfere with dental implant therapy (e.g. uncontrolled diabetes)
- 2 adjacent teeth requiring extraction
- Greater than one wall of the socket missing - assessed at time of extraction
- Any contraindications for oral surgical procedures
- Any known systemic disease affecting bone metabolism (e.g. Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis, diabetes type I and uncontrolled diabetes type II), systemic infections or recent...
- Chronic treatment (i.e., 2 weeks or more) with any medication known to affect oral status (e.g., phenytoin, dihydropyridine, calcium antagonists and cyclosporine) or bone metabolism (e.g. bisphosphonates, hormone...
- HIV or viral hepatitis;
- Physical handicaps that would interfere with the ability to perform adequate oral hygiene;
- History of local irradiation therapy in the head-neck region
- Mucosal diseases (e.g. erosive lichen planus)
- Current untreated periodontitis or gingivitis. In particular probing depths of \>4mm on one of the teeth immediately adjacent to the extraction site
- Untreated acute endodontic lesions
- Current smokers (have smoked within 3 months of study onset)
- Any known systemic disease affecting bone metabolism (e.g. Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis, diabetes type I and uncontrolled diabetes type II), systemic infections or recent...
- Self-reported alcoholism or chronic drug abuse;
- Patients suffering from a known psychological disorder or with limited mental capacity or language skills such that study information could not be understood,
- Non-compliant patients, vulnerable individuals or those unable to understand written or verbal communication and give consent.
- Pregnant or breastfeeding patients
- Involvement in current research or recent involvement in any research prior to recruitment
- Full-mouth bleeding (BOP) and plaque (PI) scores \>30% or sites with periodontal pocket depth \>5 mm at the completion of the pre-treatment phase.
The study team makes the final eligibility decision.
Where it's taking place
- London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include London, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.