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New treatment option for Rectal Neoplasms
Official title Study of Brain-Gut Function Reconstruction After Intersphincteric Resection for Ultra-Low Rectal Tumors
ClinicalTrials.gov ID: NCT06082648
What this study is testing
- What it's testing
- To investigate the effects of intersphincteric resection (ISR) of ultra-low rectal tumor on the brain-rectoanal function of patients, and to precisely localize the cerebral functional regulatory regions for intervention targets of anorectal remodeling. Utilizing transcranial magnetic stimulation(TMS) technology to explore the functional remodeling of the "new" anorectal muscle groups and provide a theoretical basis for more research on the rehabilitation and mechanism of fecal incontinence.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Primary ultra-low rectal tumor patient who is received intersphincteric resection and preventive ileostomy was performed.
- Patient who is willing to participate in the study, and voluntarily sign informed consent.
You likely can't join if
- Anastomotic leakage or other serious complications occur after surgery.
- Advanced tumor, tumor recurrence or metastasis.
- Patients with contraindications of fMRI scanning, such as history of metal implants in the body, claustrophobia, etc.
- Patients with contraindications for TMS treatment, such as intracranial metal implants, epilepsy history, heart disease with unstable heart function...
- Combined with organic brain disease and drug abuse history.
- Combined with other mental diseases.
See the full eligibility criteria
- Primary ultra-low rectal tumor patient who is received intersphincteric resection and preventive ileostomy was performed.
- Patient who is willing to participate in the study, and voluntarily sign informed consent.
- Anastomotic leakage or other serious complications occur after surgery.
- Advanced tumor, tumor recurrence or metastasis.
- Patients with contraindications of fMRI scanning, such as history of metal implants in the body, claustrophobia, etc.
- Patients with contraindications for TMS treatment, such as intracranial metal implants, epilepsy history, heart disease with unstable heart function, retinal detachment, etc.
- Combined with organic brain disease and drug abuse history.
- Combined with other mental diseases.
- Pregnant or lactating women.
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.