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New treatment option for Cannabis User
Official title Effect of Acute Exercise on Cognitive Functions and Blood Markers of Brain Plasticity in Regular Chronic Cannabis Users
ClinicalTrials.gov ID: NCT06081218
What this study is testing
- What it's testing
- The endocannabinoid system (ECS) is a complex endogenous signaling system made up of transmembrane cannabinoid receptors (CB1 and CB2 receptors), their endogenous lipid-derived ligands (the endocannabinoids - eCBs), and enzymes for ligand biosynthesis and degradation. Interestingly, exercise increase plasma AEA, one of the most famous endocannabinoid.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35. Healthy volunteers may be eligible.
You may be able to join if
- Cannabis consumer group:
- Cannabis consumption \> 100 times in lifetime, last exposure \ 10 times in the month.
- Positive toxicological urine test for ∆-9-THC.
- Having a cannabis use disorder according to the CAST. Healthy group:
- Negative urine toxicological test for cannabis.
You likely can't join if
- For all people :
- Disorders of use of other substances (alcohol, cocaine, opioid, or synthetic drugs).
- Alcohol consumption greater than 30g per day (averaged over one week) and/or alcohol abuse the week preceding the visit.
- Under medical treatment.
- Presence of diagnosed neurological disorders.
- Diagnosis of a psychotic picture entering axis I, DSM-5.
See the full eligibility criteria
- Cannabis consumer group:
- Cannabis consumption \> 100 times in lifetime, last exposure \ 10 times in the month.
- Positive toxicological urine test for ∆-9-THC.
- Having a cannabis use disorder according to the CAST. Healthy group:
- Negative urine toxicological test for cannabis.
- No regular cannabis use for more than 6 months once in a lifetime.
- No cannabis consumption in the 6 months preceding the study.
- For all people :
- Disorders of use of other substances (alcohol, cocaine, opioid, or synthetic drugs).
- Alcohol consumption greater than 30g per day (averaged over one week) and/or alcohol abuse the week preceding the visit.
- Under medical treatment.
- Presence of diagnosed neurological disorders.
- Diagnosis of a psychotic picture entering axis I, DSM-5.
- Chronic progressive disease or in remission.
- Body mass index \> 30 kg/m2 (i.e. presence of obesity).
The study team makes the final eligibility decision.
Where it's taking place
- Lille, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 35 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lille, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.