BridgeMD
Compares treatment options for Coronary Artery Disease
Official title Etomidate Versus Propofol in CABG Surgery
ClinicalTrials.gov ID: NCT06068764
What this study is testing
What is Etomidate?
Etomidate is an investigational medicine, being studied as a potential treatment for coronary artery disease.
Also referred to as Amidate™.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Patients scheduled for elective open coronary arteries bypass graft CABG surgery
- Patients with American Society of Anesthesiology (ASA) physical status score I- IV
- Patients with the ability to speak and read both English and Spanish
You likely can't join if
- Emergency CABG surgery, STAT cases, and add-on cases.
- Refusal or lack of providing the study consent
- Patients with a known current adrenocortical insufficiency
- A patient who is presenting with any kind of shock, (e.g. septic, hypovolemic, cardiogenic, etc.)
- Patients with chronic steroid use (defined as the use of glucocorticoids within 6 months preoperatively)
- Patients with a known allergy to etomidate or propofol.
See the full eligibility criteria
- Patients scheduled for elective open coronary arteries bypass graft CABG surgery
- Patients with American Society of Anesthesiology (ASA) physical status score I- IV
- Patients with the ability to speak and read both English and Spanish
- Emergency CABG surgery, STAT cases, and add-on cases.
- Refusal or lack of providing the study consent
- Patients with a known current adrenocortical insufficiency
- A patient who is presenting with any kind of shock, (e.g. septic, hypovolemic, cardiogenic, etc.)
- Patients with chronic steroid use (defined as the use of glucocorticoids within 6 months preoperatively)
- Patients with a known allergy to etomidate or propofol.
- Patients with a known seizure disorder.
- Patients who are enrolled in other clinical research studies that can compete with this study.
The study team makes the final eligibility decision.
Where it's taking place
- Hartford, Connecticut, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hartford, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.