Recruiting PHASE1 Metastatic Castration-resistant Prostate Cancer

New treatment option for Metastatic Castration-resistant Prostate Cancer

Official title A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

ClinicalTrials.gov ID: NCT06067841

What this study is testing

What is BMS-986460?

BMS-986460 is an investigational medicine, being studied as a potential treatment for metastatic castration-resistant prostate cancer.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of BMS-986460 in men with Metastatic Castration-resistant Prostate Cancer.
  • Phase 1: an early, usually small safety study

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 and older, men only

You may be able to join if

  • Participant must have histologically or cytologically confirmed adenocarcinoma of the prostate.
  • Participant must have an Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1.
  • Participant must have prostate specific antigen (PSA) of ≥ 2 ng/mL at Screening
  • Participant must have progressed on androgen deprivation therapy (ADT) and at least one prior secondary hormonal therapy approved for...

You likely can't join if

  • Participant must not have history of brain metastases.
  • Participant must not have impaired cardiac function or clinically significant cardiac disease.
  • Participant must not have any significant medical condition, including active or uncontrolled infection, psychiatric illness, or the presence of...

The study team makes the final eligibility decision.

Where it's taking place

  • Palo Alto, California, United States
  • Sarasota, Florida, United States
  • Boston, Massachusetts, United States
  • New York, New York, United States
  • Durham, North Carolina, United States
  • San Antonio, Texas, United States
  • Seattle, Washington, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling male, 18 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Palo Alto, California, United States; Sarasota, Florida, United States; Boston, Massachusetts, United States; New York, New York, United States; Durham, North Carolina, United States; San Antonio, Texas, United States and 1 more location(s). Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.