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New treatment option for Aphasia, Primary Progressive
Official title Propranolol in Primary Progressive Aphasia
ClinicalTrials.gov ID: NCT06066710
What this study is testing
What is Propranolol?
Propranolol is an investigational medicine, being studied as a potential treatment for aphasia, primary progressive.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to find out how the language of people with Primary Progressive Aphasia is affected by Propranolol. Propranolol is not FDA approved for the treatment of Primary Progressive Aphasia.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- 1\. Age: 50 and older
- 2\. Primary Progressive Aphasia diagnosis
- 3\. Native English speaker
You likely can't join if
- 1\. Unable to provide consent
- 2\. Taking alpha 2 agonists (clonidine and guanfacine)
- 3\. Other major psychological or neurological diagnosis
- 4\. Major head trauma that contributed to their condition
- 5\. Allergic reaction to adhesives
- 6\. Uncorrected vision/hearing impairments
See the full eligibility criteria
- 1\. Age: 50 and older
- 2\. Primary Progressive Aphasia diagnosis
- 3\. Native English speaker
- 1\. Unable to provide consent
- 2\. Taking alpha 2 agonists (clonidine and guanfacine)
- 3\. Other major psychological or neurological diagnosis
- 4\. Major head trauma that contributed to their condition
- 5\. Allergic reaction to adhesives
- 6\. Uncorrected vision/hearing impairments
- 7\. Diabetes
- 8\. Reactive airway disease
- 9\. Untreated hypothyroidism
- 10\. Bradyarrhythmia
- 11\. Unexplained syncope
- 12\. Pregnancy (assessed verbally on the days of MR imaging)
- 13\. Drugs that interact with propranolol, such as alpha 2 agonists
- 14\. Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker or other contraindication to MR scanning. people with any implanted device that cannot be verified as MRI...
The study team makes the final eligibility decision.
Where it's taking place
- Columbia, Missouri, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Columbia, Missouri, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.