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Compares treatment options for Intrabony Periodontal Defect
Official title Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects
ClinicalTrials.gov ID: NCT06048042
What this study is testing
What is Autogenous Demineralized Dentin Graft?
Autogenous Demineralized Dentin Graft is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for intrabony periodontal defect.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The main goal is to evaluate and compare the clinical and radiographic efficacy of autogenous demineralized dentin as bone graft substitute versus autogenous bone graft when performed with modified minimally invasive surgical technique (M-MIST) in the treatment of periodontal intrabony defects. The main question is: In periodontitis patients with intrabony defects, will using autogenous demineralized dentin as bone graft substitute result in clinical attachment gain and linear bone fill similar to autogenous bone graft following modified minimally invasive surgical technique?
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50. Healthy volunteers may be eligible.
You may be able to join if
- Patient-related criteria:
- Motivated patient 18 years of age or order.
- Patient consulting in the outpatient clinic.
- Patient ready to perform oral hygiene instructions.
- Provide informed consent.
You likely can't join if
- Patient-related criteria:
- Medically compromised patients.
- Pregnant women.
- Uncooperative patients.
- Smokers.
- Systemic diseases that may compromise healing or bone metabolism (e.g diabetes, hyperthyroidism).
See the full eligibility criteria
- Patient-related criteria:
- Motivated patient 18 years of age or order.
- Patient consulting in the outpatient clinic.
- Patient ready to perform oral hygiene instructions.
- Provide informed consent.
- Accepts the 6 months follow-up period.
- Teeth related criteria:
- Tooth with two or three-walled intra-bony defect, probing depth ≥ 5mm with intra osseous defect ≥ 3mm.
- Mature permanent tooth.
- Unrestorable tooth or fractured tooth beyond restoration, impacted third molar or supernumerary tooth to be extracted and used as whole tooth graft inside the intrabony defect.
- Patient-related criteria:
- Medically compromised patients.
- Pregnant women.
- Uncooperative patients.
- Smokers.
- Systemic diseases that may compromise healing or bone metabolism (e.g diabetes, hyperthyroidism).
- Failure to maintain good oral hygiene.
- Teeth related criteria:
- Teeth with supra-bony defects.
- Teeth with grade III mobility.
- Teeth having interproximal craters, grade III furcation involvement, and grade III mobility.
- Presence of caries or overhanging restorations.
- Presence of peri-apical injuries.
The study team makes the final eligibility decision.
Where it's taking place
- Cairo, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cairo, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.