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New treatment option for Stroke, Ischemic
Official title Vision Loss Impact on Navigation in Virtual Reality
ClinicalTrials.gov ID: NCT06047717
What this study is testing
- What it's testing
- The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 75. Healthy volunteers may be eligible.
You may be able to join if
- Cortically Blind Group:
- Residents of the United States or Canada
- Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age...
- Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.
- Willing, able, and competent to provide their own informed consent
You likely can't join if
- Those who have never driven or earned a drivers' license
- Past or present ocular disease interfering with visual acuity
- Best corrected visual acuity (BCVA) worse than 20/40 in either eye
- Sustained damage to the dorsal lateral geniculate nucleus
- Presence of diffuse, whole-brain degenerative processes
- Presence of brain damage deemed by study staff to potentially interfere with outcome measures
See the full eligibility criteria
- Cortically Blind Group:
- Residents of the United States or Canada
- Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans)
- Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.
- Willing, able, and competent to provide their own informed consent
- Cognitively able, responsible to understand written and oral instructions in English
- Emmetropic or else wear corrective contact lenses inside the virtual reality headset
- Those who have never driven or earned a drivers' license
- Past or present ocular disease interfering with visual acuity
- Best corrected visual acuity (BCVA) worse than 20/40 in either eye
- Sustained damage to the dorsal lateral geniculate nucleus
- Presence of diffuse, whole-brain degenerative processes
- Presence of brain damage deemed by study staff to potentially interfere with outcome measures
- History of traumatic brain injury
- Documented history of drug/alcohol abuse
- Diagnosis of cognitive or seizure disorders
- Diagnosis of one-sided attentional neglect Control Group: Inclusion Criteria:
- Normal or corrected-to-normal vision, who are between the ages of 21 and 75 years of age, roughly matched to the age of CB people enrolled above
- Competent and responsible, as determined by the Principal Investigator
- Willing, able, and competent to provide their own informed consent
- Normal cognitive abilities, be able to understand written and oral instructions in English
- Emmetropic or else wear corrective contact lenses inside the virtual reality headset Exclusion Criteria:
- people who have never driven or earned a drivers' license
- BCVA worse than 20/40 in either eye
- Presence of vision loss from ocular diseases or disorders
- Presence of a visual field defect
- Inability to wear corrective contact lenses inside the virtual reality helmet if required to see clearly
- people with a history of neurological disorders
- people with a history of TBI
- Persons who lack the competence or are otherwise unable to perform the visual testing as directed.
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.