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New treatment option for Psychotic Disorders
Official title EEG Microstates Across At-Risk Mental States
ClinicalTrials.gov ID: NCT06045897
What this study is testing
What is Biological sampling?
Biological sampling is an investigational medicine, given as an once-daily, being studied as a potential treatment for psychotic disorders.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this observational study is to compare subjects with at-risk-mental-state, early psychosis, schizophrenia, depression, and autism spectrum disorders, with healthy controls (N = 21 x 6). The main questions it aims to answer are: are EEG microstate anomalies associated with diagnosis, clinical and functional prognosis, both in resting conditions and during sleep ?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 15 to 30. Healthy volunteers may be eligible.
You may be able to join if
- age between 15 and 30 years
- people meeting CAARMS criteria for stage Ia or Ib mental states at risk (for stage Ia, mild or nonspecific symptoms of psychosis or severe mood...
- people meeting any DSM-5 criteria associated with a first onset of psychotic symptoms (first episode psychosis)
- people satisfying DSM-5 criteria for depressive disorder
- people meeting DSM-5 criteria for autism spectrum disorder
You likely can't join if
- suicidal risk
- severe or non-stabilized somatic and neurological disorders
- epilepsy
- head trauma
- IQ below 70
- for healthy control people, a family history of psychosis is an exclusion criterion
See the full eligibility criteria
- age between 15 and 30 years
- people meeting CAARMS criteria for stage Ia or Ib mental states at risk (for stage Ia, mild or nonspecific symptoms of psychosis or severe mood disorder, and mild functional impairment; for stage Ib, moderate symptoms...
- people meeting any DSM-5 criteria associated with a first onset of psychotic symptoms (first episode psychosis)
- people satisfying DSM-5 criteria for depressive disorder
- people meeting DSM-5 criteria for autism spectrum disorder
- healthy control people recruited from the general population
- suicidal risk
- severe or non-stabilized somatic and neurological disorders
- epilepsy
- head trauma
- IQ below 70
- for healthy control people, a family history of psychosis is an exclusion criterion
- bipolar disorder
- obsessive-compulsive disorder
- substance use disorder, except for cannabis, tolerated up to 5 joints/day.
The study team makes the final eligibility decision.
Where it's taking place
- Paris, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 15 years to 30 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Paris, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.