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Compares treatment options for Hysterectomy
Official title NAC vs Placebo on Opioid Use for Hysterectomy
ClinicalTrials.gov ID: NCT06039566
What this study is testing
What is IV N-acetylcysteine?
IV N-acetylcysteine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for hysterectomy.
Also referred to as NAC.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Inclusion
- Undergoing elective laparoscopic or robotic, full, or partial hysterectomy procedure
- 18 years of age and older Exclusion
- Less than 40kg in weight
- Unable to provide written, informed consent
See the full eligibility criteria
- Inclusion
- Undergoing elective laparoscopic or robotic, full, or partial hysterectomy procedure
- 18 years of age and older Exclusion
- Less than 40kg in weight
- Unable to provide written, informed consent
- History of an adverse or anaphylactoid reaction to acetylcysteine
- Active asthma, wheezing, or using inhaled bronchodilators
- Non-English speaking
- Insulin dependent diabetes if D5W is required
- Blood clotting disorders
The study team makes the final eligibility decision.
Where it's taking place
- Charleston, South Carolina, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Charleston, South Carolina, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.